Simparica Oral Flea and Tick Preventative for Dogs

Simparica

Overview

Simparica contains sarolaner, an isoxazoline compound that provides fast-acting, once-monthly oral protection against fleas and ticks. Sarolaner begins killing fleas within 3 hours and ticks within 8 hours of administration. Approved for dogs and puppies from eight weeks of age (weighing at least 1.25 kg), Simparica's palatable chewable tablet aids compliance. Its rapid efficacy helps reduce the risk of tick-borne diseases and flea-related dermatitis.

Key Benefits

Rapid flea and tick kill: Eliminates fleas within 3 hours and ticks within 8 hours, providing quick relief. Once-monthly convenience: One chew per month maintains continuous protection, simplifying parasite control. Waterproof advantage: Oral administration ensures efficacy regardless of bathing or swimming. Long-lasting efficacy: Provides full protection against new infestations for a full 30 days.

Usage & Dosage

Select the correct Simparica chew based on body weight:

• 1.25 – 2.5 kg: One 5 mg chew monthly.
• 2.6 – 5 kg: One 10 mg chew monthly.
• 5.1 – 10 kg: One 20 mg chew monthly.
• 10.1 – 20 kg: One 40 mg chew monthly.
• 20.1 – 40 kg: One 80 mg chew monthly.
• > 40 kg: Use appropriate combination of chews to achieve correct dose.

Administer with or without food—ensure the dog consumes the entire chew. If vomiting occurs within one hour, administer a replacement chew. Resume the 30-day schedule thereafter. Store chews in original packaging at room temperature in a secure area away from sunlight.

Safety & Considerations

Simparica is generally well tolerated; mild side effects—such as vomiting, diarrhoea, lethargy, and pruritus—are uncommon and resolve quickly. Use caution in dogs with a history of seizures, as isoxazolines may lower the seizure threshold. Do not use in puppies younger than eight weeks or dogs weighing less than 1.25 kg. Pregnant and lactating bitches can be treated under veterinary supervision. Avoid administering other isoxazole-based products concurrently to prevent additive toxicity. Keep chews out of reach of children and other pets. In the event of overdose or severe adverse reactions, seek veterinary assistance immediately.

Frequently asked questions

How quickly does Simparica start killing fleas?

Simparica begins killing over 90% of adult fleas within 3 hours of administration and eliminates most fleas within 8 hours.

Is Simparica effective against all ticks?

Yes—Simparica kills a broad range of tick species, including Ixodes scapularis, Rhipicephalus sanguineus, and Dermacentor variabilis.

Can I give Simparica with food?

Yes—Simparica can be administered with or without food; feeding may reduce the chance of gastrointestinal upset.

What if my dog vomits the chew?

If vomiting occurs within one hour, administer a replacement chew. If after one hour, no replacement is needed—resume the monthly schedule.

Is Simparica safe for puppies?

Yes—approved for puppies from eight weeks of age and weighing at least 1.25 kg.