Credelio Plus Flea, Tick, and Heartworm Preventative

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Credelio Plus

Product Overview

Credelio Plus combines lotilaner (for flea and tick control) with milbemycin oxime (for heartworm and intestinal worm prevention) in a single chewable tablet. Lotilaner begins killing fleas within 4 hours and ticks within 8 hours, providing one month of continuous protection. Milbemycin oxime prevents heartworm disease and treats roundworms, hookworms, and whipworms. Credelio Plus is approved for dogs from 8 weeks old (weighing at least 2 kg), ensuring comprehensive parasite defence with a single monthly chew.

Key Benefits

Rapid flea and tick kill: Lotilaner kills fleas in 4 hours and ticks (including Ixodes, Rhipicephalus, and Dermacentor) in 8 hours, helping prevent tick-borne diseases. Broad-spectrum parasite control: Milbemycin oxime prevents heartworm and combats common gastrointestinal nematodes. Once-monthly dosing: One chewable tablet provides 30 days of continuous protection, streamlining parasite prevention routines. Highly palatable: Beef-flavoured chew that encourages voluntary ingestion—no need for force-feeding.

Usage & Dosage

Select the correct Credelio Plus tablet based on body weight:

  • Credelio Plus 112.5 mg/10 mg (2 – 5 kg): One chew monthly.
  • Credelio Plus 225 mg/20 mg (5 – 10 kg): One chew monthly.
  • Credelio Plus 450 mg/40 mg (10 – 20 kg): One chew monthly.
  • Credelio Plus 900 mg/80 mg (20 – 40 kg): One chew monthly.
  • Credelio Plus 1125 mg/100 mg (40 – 56 kg): One chew monthly.
  • Credelio Plus 1500 mg/133 mg (56 – 78 kg): One chew monthly.
Administer once every 30 days with or without food. Ensure the dog consumes the full chew; do not break or split the tablet. In the event of vomiting within 1 hour of dosing, re-dose with another full tablet. If vomiting occurs after 1 hour, no re-dose is necessary; continue the regular monthly schedule. Maintain consistent monthly administration for uninterrupted protection.

Safety & Considerations

Credelio Plus is well tolerated; common adverse reactions include vomiting, diarrhoea, lethargy, and decreased appetite—usually mild and transient. Use caution in dogs with a history of seizures; lotilaner may lower seizure threshold in predisposed dogs. Credelio Plus is not intended for use in puppies under 8 weeks of age or dogs under 2 kg. Pregnant or lactating bitches should be treated only under veterinary supervision. Perform an annual heartworm test before starting Credelio Plus. Do not use Credelio Plus on dogs that test positive for heartworm. Store chews in their original packaging in a cool, dry place, out of sight and reach of children and other pets.

Frequently asked questions

How soon does Credelio Plus kill fleas?
Credelio Plus begins killing fleas within 4 hours of administration and provides at least 30 days of continuous protection.
Can I give Credelio Plus with food?
Yes—Credelio Plus can be administered with or without food. Offering with food may enhance palatability and reduce gastrointestinal side effects.
What if my dog vomits within 1 hour?
If vomiting occurs within 1 hour of administration, administer a replacement chew. If after 1 hour, no re-dose is required—resume the normal monthly schedule.
Does Credelio Plus treat ticks?
Yes—Credelio Plus kills multiple tick species (Ixodes, Rhipicephalus, Dermacentor) within 8 hours, reducing the risk of tick-borne diseases.
Is Credelio Plus suitable for small puppies?
Credelio Plus is approved for puppies from 8 weeks of age and weighing at least 2 kg. For younger or smaller puppies, consult your veterinarian for alternative options.

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