Dog Heartworm Prevention Medicine

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NexGard Spectra Dog Extra Large 30.1-60kg Red Front
As low as $32.08
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NexGard Spectra Dog Large 15.1-30kg Purple New
As low as $30.56
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NexGard Spectra Dog Medium 7.6-15kg Green Front
As low as $28.88
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Mavlab Dimmitrol Dog 200mg Tablets
As low as $21.64
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NexGard Spectra Dog Very Small 2-3.5kg Orange
As low as $24.14
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Simparica Trio Dog Extra Large 40.1 - 60kg Red
As low as $77.86
3 options available
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Simparica Trio Dog Large 20.1 - 40kg Green
As low as $74.26
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Simparica Trio Dog Medium 10.1 - 20kg Blue
As low as $70.66
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Simparica Trio Chews for Dogs 5.1-10kg Orange Small
As low as $67.37
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Moxiclear Puppies & Small Dogs Up To 4kg Green 3 Pack View Product
Simparica Trio Dog Puppies 1.25 - 2.5kg Yellow 3 Chews View Product
Milbemax Allwormer Dog Large 5-25Kg
As low as $21.90
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Milbemax Allwormer Dog Small 0.5-5kg
As low as $8.95
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Moxiclear Dogs Over 25kg Pink
As low as $50.22
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Credelio Plus Dog Small 2.8-5.5kg Pink
As low as $25.25
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Credelio Plus Dog Medium 5.5-11kg Orange
As low as $27.02
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Credelio Plus Dog Large 11-22kg Green
As low as $28.43
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Valuheart Heartworm Tablets Small Dogs up to 10kg Blue View Product
Valuheart Heartworm Tablets Dog Medium 11-20kg Green
As low as $16.96
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Advocate Dog Extra Large over 25kg Blue
As low as $91.16
3 options available
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Advocate Dog Large 10-25kg Red
As low as $81.26
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Valuheart Heartworm Tablets Dog Large 21-40kg Gold
As low as $18.92
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Advocate Puppy & Dog Small Up To 4kg Green
As low as $71.10
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Credelio Plus Dog Very Small 1.4-2.8kg Yellow 1 Pack View Product

Heartworm Prevention for Dogs

Why Heartworm Prevention Is Essential

Heartworm disease, caused by Dirofilaria immitis, can be fatal if left untreated. Mosquitoes transmit immature heartworms that mature in a dog's heart and pulmonary arteries, leading to coughing, reduced exercise tolerance, and congestive heart failure. Treatment is costly, invasive, and carries risks of severe side effects. Preventing heartworm infection is far safer and more economical. Even indoor dogs are at risk—mosquitoes can enter homes through open windows. Annual testing and consistent prophylaxis are critical components of responsible canine healthcare.

Our Leading Heartworm Preventatives

We offer several vet-recommended heartworm preventatives, including Advocate, NexGard Spectra, and Simparica Trio. Advocate® spot-on treatment provides monthly heartworm prevention along with control of fleas and intestinal worms. NexGard Spectra® chewables combine monthly flea and tick control with heartworm prevention and broad-spectrum worming (including roundworms and hookworms). Simparica Trio® also delivers comprehensive monthly protection against heartworm, fleas, ticks, and intestinal parasites. Each product is palatable, easy to administer, and has a proven safety profile when used according to instructions.

Selecting a Heartworm Prevention Plan

Choose a product that fits your dog's lifestyle, size, and tolerance. Puppies (from 8 weeks) weighing at least 2 kg can start on chewables like NexGard Spectra® or Simparica Trio®. Advocate® spot-on is suitable from 7 weeks old and 1 kg body weight. For multi-parasite protection, Simparica Trio® or NexGard Spectra® may be most convenient, reducing the number of separate treatments required. Always test for existing heartworm infection before starting a preventer—administering prevention to an infected dog can cause serious reactions. Consult your veterinarian for an annual antigen test and follow label instructions meticulously.

Administration & Monitoring

Administer chewables with or without food at the recommended dose based on weight. For Advocate® spot-on, apply monthly to the skin at the base of the neck, avoiding contact with water for 48 hours. Keep a calendar reminder for dosing dates and schedule annual veterinary check-ups and heartworm tests to confirm negative status. Even with prevention, watch for signs such as fatigue, persistent coughing, or difficulty breathing, and seek veterinary care immediately if symptoms arise. Store heartworm preventatives out of reach of children and pets to prevent accidental ingestion.

Frequently asked questions

When should I start heartworm prevention?
Begin puppies on prevention at 8 weeks old, but first ensure they test negative for heartworm; continue monthly year-round.
Can I give heartworm preventatives with other parasite treatments?
Yes—Advocate®, NexGard Spectra®, and Simparica Trio® combine multiple preventatives, reducing the need for separate products; always follow label instructions.
What happens if I miss a dose?
Administer as soon as possible, then resume the regular schedule. Consult your vet if dosing is more than one month late, as testing may be required.
Can indoor dogs get heartworm?
Yes—mosquitoes can enter homes, so indoor dogs remain at risk and should receive year-round prevention.
How often should I test for heartworm?
Test annually—ideally before starting prevention each spring and again 6 months after the last dose to ensure efficacy.

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